D

Diglyme

IUPAC: 1-methoxy-2-(2-methoxyethoxy)ethane

C6H14O3 Solvents CAS 111-96-6
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Quick Reference
Formula / NotationC6H14O3
CAS Number111-96-6
Molecular Weight134.17
Melting Point-90 °F (NTP, 1992)
Boiling Point321 to 324 °F at 760 mmHg ; 241 °F at 200 mmHg; 167 °F at 35 mmHg; 68 °F at 3 mmHg (NTP, 1992)
Density0.945 at 68 °F (USCG, 1999) - Less dense than water; will float
SolubilityMiscible (NTP, 1992)
AppearanceDiethylene glycol dimethyl ether is a colorless watery liquid with a pleasant odor. Floats and mixes with water. (USCG, 1999)
Also Known As1-methoxy-2-(2-methoxyethoxy)ethane; 111-96-6; 1-Methoxy-2-(2-methoxyethoxy)ethane; Bis(2-methoxyethyl) ether; DIETHYLENE GLYCOL DIMETHYL ETHER; 2,5,8-Trioxanonane; Dimethyl carbitol; Di(2-Methoxyethyl) ether; Bis(2-methoxyethyl)ether; Glyme 2
CategorySolvents

What is Diglyme?

Diglyme is a polyether that is the dimethyl ether derivative of diethylene glycol. It has a role as a xenobiotic, a solvent and an environmental contaminant. It is functionally related to a diethylene glycol.

Formula & Notation

C6H14O3

IUPAC Name: 1-methoxy-2-(2-methoxyethoxy)ethane

Other Names / Synonyms: 1-methoxy-2-(2-methoxyethoxy)ethane; 111-96-6; 1-Methoxy-2-(2-methoxyethoxy)ethane; Bis(2-methoxyethyl) ether; DIETHYLENE GLYCOL DIMETHYL ETHER; 2,5,8-Trioxanonane; Dimethyl carbitol; Di(2-Methoxyethyl) ether; Bis(2-methoxyethyl)ether; Glyme 2

Properties & Characteristics

Appearance: Diethylene glycol dimethyl ether is a colorless watery liquid with a pleasant odor. Floats and mixes with water. (USCG, 1999). Molecular formula: C6H14O3. Molecular weight: 134.17 g/mol. Boiling point: 321 to 324 °F at 760 mmHg ; 241 °F at 200 mmHg; 167 °F at 35 mmHg; 68 °F at 3 mmHg (NTP, 1992). Melting point: -90 °F (NTP, 1992). Density: 0.945 at 68 °F (USCG, 1999) - Less dense than water; will float. Solubility: Miscible (NTP, 1992). Vapor pressure: 2.96 [mmHg]. LogP: -0.4.

Physical Data

PropertyValue
Melting Point-90 °F (NTP, 1992)
Boiling Point321 to 324 °F at 760 mmHg ; 241 °F at 200 mmHg; 167 °F at 35 mmHg; 68 °F at 3 mmHg (NTP, 1992)
Density0.945 at 68 °F (USCG, 1999) - Less dense than water; will float
Molecular Weight134.17
SolubilityMiscible (NTP, 1992)
AppearanceDiethylene glycol dimethyl ether is a colorless watery liquid with a pleasant odor. Floats and mixes with water. (USCG, 1999)

Uses & Applications

Used as a reaction solvent in organic synthesis, extraction solvent, cleaning agent, or in pharmaceutical manufacture.

Safety Information

Flammable solvent. Keep away from heat, sparks, and open flame. Use in well-ventilated area or fume hood. Consult SDS before use.

Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.

Key Facts

Term Diglyme
Formula C6H14O3
CAS Number 111-96-6
Molecular Weight 134.17
Category Solvents
Synonyms 1-methoxy-2-(2-methoxyethoxy)ethane; 111-96-6; 1-Methoxy-2-(2-methoxyethoxy)ethane; Bis(2-methoxyethyl) ether; DIETHYLENE GLYCOL DIMETHYL ETHER; 2,5,8-Trioxanonane; Dimethyl carbitol; Di(2-Methoxyethyl) ether; Bis(2-methoxyethyl)ether; Glyme 2

Frequently Asked Questions

Diglyme is a polyether that is the dimethyl ether derivative of diethylene glycol. It has a role as a xenobiotic, a solvent and an environmental contaminant. It is functionally related to a diethylene glycol.

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Editorial standards: Chemical data is sourced from peer-reviewed literature, CAS Registry, NIST WebBook, and PubChem. Safety information reflects guidance from OSHA, ECHA, and IAEA. For educational purposes only — always consult official SDS documentation and qualified professionals before handling chemicals.