D

1,4-Dioxane

IUPAC: 1,4-dioxane

C4H8O2 Solvents CAS 123-91-1
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Quick Reference
Formula / NotationC4H8O2
CAS Number123-91-1
Molecular Weight88.11
Melting Point53.2 °F (NTP, 1992)
Boiling Point214 °F at 760 mmHg (NTP, 1992)
Density1.036 at 68 °F (USCG, 1999) - Denser than water; will sink
Solubilitygreater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
AppearanceDioxane appears as a clear colorless liquid with a faint ethereal odor. Flash point 55 °F. Slightly denser than water and soluble in water. Vapors heavier than air. Susceptible to autooxidation to...
Also Known AsDioxane; 123-91-1; p-Dioxane; Diethylene ether; 1,4-Diethylene dioxide; 1,4-Dioxacyclohexane; Dioxan; Tetrahydro-1,4-dioxin; Tetrahydro-p-dioxin; Di(ethylene oxide)
CategorySolvents

What is 1,4-Dioxane?

1,4-Dioxane can cause cancer according to an independent committee of scientific and health experts.

Formula & Notation

C4H8O2

IUPAC Name: 1,4-dioxane

Other Names / Synonyms: Dioxane; 123-91-1; p-Dioxane; Diethylene ether; 1,4-Diethylene dioxide; 1,4-Dioxacyclohexane; Dioxan; Tetrahydro-1,4-dioxin; Tetrahydro-p-dioxin; Di(ethylene oxide)

Properties & Characteristics

Appearance: Dioxane appears as a clear colorless liquid with a faint ethereal odor. Flash point 55 °F. Slightly denser than water and soluble in water. Vapors heavier than air. Susceptible to autooxidation to.... Molecular formula: C4H8O2. Molecular weight: 88.11 g/mol. Boiling point: 214 °F at 760 mmHg (NTP, 1992). Melting point: 53.2 °F (NTP, 1992). Density: 1.036 at 68 °F (USCG, 1999) - Denser than water; will sink. Solubility: greater than or equal to 100 mg/mL at 68 °F (NTP, 1992). Vapor pressure: 29 mmHg at 68 °F ; 37 mmHg at 77 °F (NTP, 1992). LogP: -0.3.

Physical Data

PropertyValue
Melting Point53.2 °F (NTP, 1992)
Boiling Point214 °F at 760 mmHg (NTP, 1992)
Density1.036 at 68 °F (USCG, 1999) - Denser than water; will sink
Molecular Weight88.11
Solubilitygreater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
AppearanceDioxane appears as a clear colorless liquid with a faint ethereal odor. Flash point 55 °F. Slightly denser than water and soluble in water. Vapors heavier than air. Susceptible to autooxidation to...

Uses & Applications

Used as a reaction solvent in organic synthesis, extraction solvent, cleaning agent, or in pharmaceutical manufacture.

Safety Information

Flammable solvent. Keep away from heat, sparks, and open flame. Use in well-ventilated area or fume hood. Consult SDS before use.

Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.

Key Facts

Term 1,4-Dioxane
Formula C4H8O2
CAS Number 123-91-1
Molecular Weight 88.11
Category Solvents
Synonyms Dioxane; 123-91-1; p-Dioxane; Diethylene ether; 1,4-Diethylene dioxide; 1,4-Dioxacyclohexane; Dioxan; Tetrahydro-1,4-dioxin; Tetrahydro-p-dioxin; Di(ethylene oxide)

Frequently Asked Questions

1,4-Dioxane can cause cancer according to an independent committee of scientific and health experts.

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Editorial standards: Chemical data is sourced from peer-reviewed literature, CAS Registry, NIST WebBook, and PubChem. Safety information reflects guidance from OSHA, ECHA, and IAEA. For educational purposes only — always consult official SDS documentation and qualified professionals before handling chemicals.