T

Tetrahydrofuran

IUPAC: oxolane

C4H8O Solvents CAS 109-99-9
Expert Written | Fact Checked | Sources Cited | AllChemicals Editorial Team
Quick Reference
Formula / NotationC4H8O
CAS Number109-99-9
Molecular Weight72.11
Melting Point-163.3 °F (NTP, 1992)
Boiling Point151 °F at 760 mmHg (NTP, 1992)
Density0.888 at 68 °F (USCG, 1999) - Less dense than water; will float
Solubilitygreater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
AppearanceTetrahydrofuran appears as a clear colorless liquid with an ethereal odor. Less dense than water. Flash point 6 °F. Vapors are heavier than air.
Also Known Asoxolane; Oxolane; 109-99-9; Furanidine; Furan, tetrahydro-; Tetramethylene oxide; Hydrofuran; Oxacyclopentane; 1,4-Epoxybutane; Tetrahydrofuranne
CategorySolvents

What is Tetrahydrofuran?

Tetrahydrofuran can cause cancer according to California Labor Code and the World Health Organization's International Agency for Research on Cancer (IARC).

Formula & Notation

C4H8O

IUPAC Name: oxolane

Other Names / Synonyms: oxolane; Oxolane; 109-99-9; Furanidine; Furan, tetrahydro-; Tetramethylene oxide; Hydrofuran; Oxacyclopentane; 1,4-Epoxybutane; Tetrahydrofuranne

Properties & Characteristics

Appearance: Tetrahydrofuran appears as a clear colorless liquid with an ethereal odor. Less dense than water. Flash point 6 °F. Vapors are heavier than air.. Molecular formula: C4H8O. Molecular weight: 72.11 g/mol. Boiling point: 151 °F at 760 mmHg (NTP, 1992). Melting point: -163.3 °F (NTP, 1992). Density: 0.888 at 68 °F (USCG, 1999) - Less dense than water; will float. Solubility: greater than or equal to 100 mg/mL at 68 °F (NTP, 1992). Vapor pressure: 114 mmHg at 59 °F ; 145 mmHg at 68 °F (NTP, 1992). LogP: 0.5.

Physical Data

PropertyValue
Melting Point-163.3 °F (NTP, 1992)
Boiling Point151 °F at 760 mmHg (NTP, 1992)
Density0.888 at 68 °F (USCG, 1999) - Less dense than water; will float
Molecular Weight72.11
Solubilitygreater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
AppearanceTetrahydrofuran appears as a clear colorless liquid with an ethereal odor. Less dense than water. Flash point 6 °F. Vapors are heavier than air.

Uses & Applications

Used as a reaction solvent in organic synthesis, extraction solvent, cleaning agent, or in pharmaceutical manufacture.

Safety Information

Flammable solvent. Keep away from heat, sparks, and open flame. Use in well-ventilated area or fume hood. Consult SDS before use.

Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.

Key Facts

Term Tetrahydrofuran
Formula C4H8O
CAS Number 109-99-9
Molecular Weight 72.11
Category Solvents
Synonyms oxolane; Oxolane; 109-99-9; Furanidine; Furan, tetrahydro-; Tetramethylene oxide; Hydrofuran; Oxacyclopentane; 1,4-Epoxybutane; Tetrahydrofuranne

Frequently Asked Questions

Tetrahydrofuran can cause cancer according to California Labor Code and the World Health Organization's International Agency for Research on Cancer (IARC).

More "T" Terms

View all "T" terms →
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Editorial standards: Chemical data is sourced from peer-reviewed literature, CAS Registry, NIST WebBook, and PubChem. Safety information reflects guidance from OSHA, ECHA, and IAEA. For educational purposes only — always consult official SDS documentation and qualified professionals before handling chemicals.