D

D-Mannitol

IUPAC: (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol

C6H14O6 Organic Compounds CAS 69-65-8
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Quick Reference
Formula / NotationC6H14O6
CAS Number69-65-8
Molecular Weight182.17
Melting Point331 to 334 °F (NTP, 1992)
Boiling Point563 °F at 3.5 mmHg (NTP, 1992)
Density1.489 at 68 °F (NTP, 1992) - Denser than water; will sink
Solubilitygreater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
AppearanceD-mannitol appears as odorless white crystalline powder or free-flowing granules. Sweet taste. (NTP, 1992)
Also Known As(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol; mannitol; 69-65-8; Mannite; Osmitrol; Manna sugar; Cordycepic acid; Diosmol; Resectisol; Mannidex
CategoryOrganic Compounds

What is D-Mannitol?

D-mannitol is the D-enantiomer of mannitol. It has a role as a member of compatible osmolytes, a metabolite, an antiglaucoma drug, an osmotic diuretic, a sweetening agent, an allergen, a hapten, an Escherichia coli metabolite, a food anticaking agent, a food stabiliser, a food humectant, a food thickening agent and a food bulking agent.

Formula & Notation

C6H14O6

IUPAC Name: (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol

Other Names / Synonyms: (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol; mannitol; 69-65-8; Mannite; Osmitrol; Manna sugar; Cordycepic acid; Diosmol; Resectisol; Mannidex

Properties & Characteristics

Appearance: D-mannitol appears as odorless white crystalline powder or free-flowing granules. Sweet taste. (NTP, 1992). Molecular formula: C6H14O6. Molecular weight: 182.17 g/mol. Boiling point: 563 °F at 3.5 mmHg (NTP, 1992). Melting point: 331 to 334 °F (NTP, 1992). Density: 1.489 at 68 °F (NTP, 1992) - Denser than water; will sink. Solubility: greater than or equal to 100 mg/mL at 68 °F (NTP, 1992). LogP: -3.1.

Physical Data

PropertyValue
Melting Point331 to 334 °F (NTP, 1992)
Boiling Point563 °F at 3.5 mmHg (NTP, 1992)
Density1.489 at 68 °F (NTP, 1992) - Denser than water; will sink
Molecular Weight182.17
Solubilitygreater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
AppearanceD-mannitol appears as odorless white crystalline powder or free-flowing granules. Sweet taste. (NTP, 1992)

Uses & Applications

Used as an industrial feedstock, solvent, pharmaceutical intermediate, flavoring agent, or chemical building block.

Safety Information

Flammable or irritant. Many organic compounds are flammable liquids or vapours. Keep away from ignition sources. Consult SDS for specific hazard data.

Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.

Key Facts

Term D-Mannitol
Formula C6H14O6
CAS Number 69-65-8
Molecular Weight 182.17
Synonyms (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol; mannitol; 69-65-8; Mannite; Osmitrol; Manna sugar; Cordycepic acid; Diosmol; Resectisol; Mannidex

Frequently Asked Questions

D-mannitol is the D-enantiomer of mannitol. It has a role as a member of compatible osmolytes, a metabolite, an antiglaucoma drug, an osmotic diuretic, a sweetening agent, an allergen, a hapten, an Escherichia coli metabolite, a food anticaking agent, a food stabiliser, a food humectant, a food thickening agent and a food bulking agent.

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Editorial standards: Chemical data is sourced from peer-reviewed literature, CAS Registry, NIST WebBook, and PubChem. Safety information reflects guidance from OSHA, ECHA, and IAEA. For educational purposes only — always consult official SDS documentation and qualified professionals before handling chemicals.