L

L-Histidine

IUPAC: (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid

C6H9N3O2 Organic Compounds CAS 71-00-1
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Quick Reference
Formula / NotationC6H9N3O2
CAS Number71-00-1
Molecular Weight155.15
Melting Point287 dec °C
Solubility45600 mg/L (at 25 °C)
AppearanceSolid; [Merck Index] Powder; [Sigma-Aldrich MSDS]
Also Known As(2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid; histidine; 71-00-1; glyoxaline-5-alanine; L-(-)-Histidine; histidina; Istidina; HISTIDINE, L-; L-Histidin; (2S)-2-amino-3-(1H-imidazol-4-yl)propanoic acid
CategoryOrganic Compounds

What is L-Histidine?

L-histidine is the L-enantiomer of the amino acid histidine. It has a role as a micronutrient, a nutraceutical, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a human metabolite and an algal metabolite. It is a L-alpha-amino acid, a histidine and a proteinogenic amino acid. It is a conjugate base of a L-histidinium(1+). It is a conjugate acid of a L-histidinate(1-). It is an enantiomer of a D-histidine. It is a tautomer of a L-histidine zwitterion.

Formula & Notation

C6H9N3O2

IUPAC Name: (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid

Other Names / Synonyms: (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid; histidine; 71-00-1; glyoxaline-5-alanine; L-(-)-Histidine; histidina; Istidina; HISTIDINE, L-; L-Histidin; (2S)-2-amino-3-(1H-imidazol-4-yl)propanoic acid

Properties & Characteristics

Appearance: Solid; [Merck Index] Powder; [Sigma-Aldrich MSDS]. Molecular formula: C6H9N3O2. Molecular weight: 155.15 g/mol. Melting point: 287 dec °C. Solubility: 45600 mg/L (at 25 °C). Vapor pressure: 0.00000001 [mmHg]. LogP: -3.2.

Physical Data

PropertyValue
Melting Point287 dec °C
Molecular Weight155.15
Solubility45600 mg/L (at 25 °C)
AppearanceSolid; [Merck Index] Powder; [Sigma-Aldrich MSDS]

Uses & Applications

Used as an industrial feedstock, solvent, pharmaceutical intermediate, flavoring agent, or chemical building block.

Safety Information

Flammable or irritant. Many organic compounds are flammable liquids or vapours. Keep away from ignition sources. Consult SDS for specific hazard data.

Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.

Key Facts

Term L-Histidine
Formula C6H9N3O2
CAS Number 71-00-1
Molecular Weight 155.15
Synonyms (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid; histidine; 71-00-1; glyoxaline-5-alanine; L-(-)-Histidine; histidina; Istidina; HISTIDINE, L-; L-Histidin; (2S)-2-amino-3-(1H-imidazol-4-yl)propanoic acid

Frequently Asked Questions

L-histidine is the L-enantiomer of the amino acid histidine. It has a role as a micronutrient, a nutraceutical, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a human metabolite and an algal metabolite. It is a L-alpha-amino acid, a histidine and a proteinogenic amino acid. It is a conjugate base of a L-histidinium(1+). It is a conjugate acid of a L-histidinate(1-). It is an enantiomer of a D-histidine. It is a tautomer of a L-histidine zwitterion.

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Editorial standards: Chemical data is sourced from peer-reviewed literature, CAS Registry, NIST WebBook, and PubChem. Safety information reflects guidance from OSHA, ECHA, and IAEA. For educational purposes only — always consult official SDS documentation and qualified professionals before handling chemicals.