B

Biotin

IUPAC: 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid

C10H16N2O3S Organic Compounds CAS 58-85-5
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Quick Reference
Formula / NotationC10H16N2O3S
CAS Number58-85-5
Molecular Weight244.31
Melting Point232 dec °C
Solubility220 mg/L (at 25 °C)
AppearanceSolid; [Merck Index] White powder; [Sigma-Aldrich MSDS]
Also Known As5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid; d-biotin; 58-85-5; vitamin H; Vitamin B7; Bioepiderm; coenzyme R; Factor S; Bios II; D(+)-Biotin
CategoryOrganic Compounds

What is Biotin?

Biotin is an organic heterobicyclic compound that consists of 2-oxohexahydro-1H-thieno[3,4-d]imidazole having a valeric acid substituent attached to the tetrahydrothiophene ring. The parent of the class of biotins. It has a role as a coenzyme, a cofactor, a prosthetic group, a nutraceutical, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a human metabolite and a fundamental metabolite. It is a vitamin B7 and a member of biotins. It is a conjugate acid of a biotinate.

Formula & Notation

C10H16N2O3S

IUPAC Name: 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid

Other Names / Synonyms: 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid; d-biotin; 58-85-5; vitamin H; Vitamin B7; Bioepiderm; coenzyme R; Factor S; Bios II; D(+)-Biotin

Properties & Characteristics

Appearance: Solid; [Merck Index] White powder; [Sigma-Aldrich MSDS]. Molecular formula: C10H16N2O3S. Molecular weight: 244.31 g/mol. Melting point: 232 dec °C. Solubility: 220 mg/L (at 25 °C). Vapor pressure: 0.00000001 [mmHg]. LogP: 0.3.

Physical Data

PropertyValue
Melting Point232 dec °C
Molecular Weight244.31
Solubility220 mg/L (at 25 °C)
AppearanceSolid; [Merck Index] White powder; [Sigma-Aldrich MSDS]

Uses & Applications

Used as an industrial feedstock, solvent, pharmaceutical intermediate, flavoring agent, or chemical building block.

Safety Information

Flammable or irritant. Many organic compounds are flammable liquids or vapours. Keep away from ignition sources. Consult SDS for specific hazard data.

Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.

Key Facts

Term Biotin
Formula C10H16N2O3S
CAS Number 58-85-5
Molecular Weight 244.31
Synonyms 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid; d-biotin; 58-85-5; vitamin H; Vitamin B7; Bioepiderm; coenzyme R; Factor S; Bios II; D(+)-Biotin

Frequently Asked Questions

Biotin is an organic heterobicyclic compound that consists of 2-oxohexahydro-1H-thieno[3,4-d]imidazole having a valeric acid substituent attached to the tetrahydrothiophene ring. The parent of the class of biotins. It has a role as a coenzyme, a cofactor, a prosthetic group, a nutraceutical, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a human metabolite and a fundamental metabolite. It is a vitamin B7 and a member of biotins. It is a conjugate acid of a biotinate.

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Editorial standards: Chemical data is sourced from peer-reviewed literature, CAS Registry, NIST WebBook, and PubChem. Safety information reflects guidance from OSHA, ECHA, and IAEA. For educational purposes only — always consult official SDS documentation and qualified professionals before handling chemicals.