B

1,4-Butanediol

IUPAC: butane-1,4-diol

C4H10O2 Organic Compounds CAS 110-63-4
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Quick Reference
Formula / NotationC4H10O2
CAS Number110-63-4
Molecular Weight90.12
Melting Point61 °F (NTP, 1992)
Boiling Point446 °F at 760 mmHg (NTP, 1992)
Density1.017 at 68 °F (USCG, 1999) - Denser than water; will sink
Solubilitygreater than or equal to 100 mg/mL at 73 °F (NTP, 1992)
Appearance1,4-butanediol appears as odorless colorless liquid or solid (depending upon temperature). (USCG, 1999)
Also Known Asbutane-1,4-diol; Butane-1,4-diol; 110-63-4; Tetramethylene glycol; 1,4-Butylene glycol; 1,4-Dihydroxybutane; 1,4-Tetramethylene glycol; Sucol B; Tetramethylene 1,4-diol; DIOL 14B
CategoryOrganic Compounds

What is 1,4-Butanediol?

Butane-1,4-diol is a butanediol that is butane in which one hydrogen of each of the methyl groups is substituted by a hydroxy group. A colourless, water-miscible, viscous liquid at room temperature (m.p. 16C) with a high boiling point (230C), it is mainly used for the production of other organic chemicals, particularly the solvent oxolane (also known as tetrahydrofuran or THF). It has a role as a protic solvent, a prodrug and a neurotoxin. It is a glycol and a butanediol.

Formula & Notation

C4H10O2

IUPAC Name: butane-1,4-diol

Other Names / Synonyms: butane-1,4-diol; Butane-1,4-diol; 110-63-4; Tetramethylene glycol; 1,4-Butylene glycol; 1,4-Dihydroxybutane; 1,4-Tetramethylene glycol; Sucol B; Tetramethylene 1,4-diol; DIOL 14B

Properties & Characteristics

Appearance: 1,4-butanediol appears as odorless colorless liquid or solid (depending upon temperature). (USCG, 1999). Molecular formula: C4H10O2. Molecular weight: 90.12 g/mol. Boiling point: 446 °F at 760 mmHg (NTP, 1992). Melting point: 61 °F (NTP, 1992). Density: 1.017 at 68 °F (USCG, 1999) - Denser than water; will sink. Solubility: greater than or equal to 100 mg/mL at 73 °F (NTP, 1992). Vapor pressure: less than 1 mmHg at 100 °F (NTP, 1992). LogP: -0.8.

Physical Data

PropertyValue
Melting Point61 °F (NTP, 1992)
Boiling Point446 °F at 760 mmHg (NTP, 1992)
Density1.017 at 68 °F (USCG, 1999) - Denser than water; will sink
Molecular Weight90.12
Solubilitygreater than or equal to 100 mg/mL at 73 °F (NTP, 1992)
Appearance1,4-butanediol appears as odorless colorless liquid or solid (depending upon temperature). (USCG, 1999)

Uses & Applications

Used as an industrial feedstock, solvent, pharmaceutical intermediate, flavoring agent, or chemical building block.

Safety Information

Flammable or irritant. Many organic compounds are flammable liquids or vapours. Keep away from ignition sources. Consult SDS for specific hazard data.

Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.

Key Facts

Term 1,4-Butanediol
Formula C4H10O2
CAS Number 110-63-4
Molecular Weight 90.12
Synonyms butane-1,4-diol; Butane-1,4-diol; 110-63-4; Tetramethylene glycol; 1,4-Butylene glycol; 1,4-Dihydroxybutane; 1,4-Tetramethylene glycol; Sucol B; Tetramethylene 1,4-diol; DIOL 14B

Frequently Asked Questions

Butane-1,4-diol is a butanediol that is butane in which one hydrogen of each of the methyl groups is substituted by a hydroxy group. A colourless, water-miscible, viscous liquid at room temperature (m.p. 16C) with a high boiling point (230C), it is mainly used for the production of other organic chemicals, particularly the solvent oxolane (also known as tetrahydrofuran or THF). It has a role as a protic solvent, a prodrug and a neurotoxin. It is a glycol and a butanediol.

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Editorial standards: Chemical data is sourced from peer-reviewed literature, CAS Registry, NIST WebBook, and PubChem. Safety information reflects guidance from OSHA, ECHA, and IAEA. For educational purposes only — always consult official SDS documentation and qualified professionals before handling chemicals.