T

tert-Butyldimethylsilyl chloride

IUPAC: tert-butyl-chloro-dimethylsilane

C6H15ClSi Laboratory Reagents CAS 18162-48-6
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Quick Reference
Formula / NotationC6H15ClSi
CAS Number18162-48-6
Molecular Weight150.72
AppearanceWhite hygroscopic solid; [Merck Index] White crystals with a pungent odor; [Alfa Aesar MSDS]
Also Known Astert-butyl-chloro-dimethylsilane; 18162-48-6; tert-Butyldimethylchlorosilane; t-Butyldimethylchlorosilane; TBDMS chloride; Silane, chloro(1,1-dimethylethyl)dimethyl-; Chloro-tert-butyldimethylsilane; 2-(chlorodimethylsilyl)-2-methylpropane; 550OPF5Z9F; CHEBI:85071
CategoryLaboratory Reagents

What is tert-Butyldimethylsilyl chloride?

Tert-butyldimethylsilyl chloride is a silyl chloride consisting of a central silicon atom covalently bound to one chloro, one tert-butyl and two methyl groups. tert-Butyldimethylsilyl chloride is a derivatisation agent used in gas chromatography/mass spectrometry applications. It has a role as a chromatographic reagent.

Formula & Notation

C6H15ClSi

IUPAC Name: tert-butyl-chloro-dimethylsilane

Other Names / Synonyms: tert-butyl-chloro-dimethylsilane; 18162-48-6; tert-Butyldimethylchlorosilane; t-Butyldimethylchlorosilane; TBDMS chloride; Silane, chloro(1,1-dimethylethyl)dimethyl-; Chloro-tert-butyldimethylsilane; 2-(chlorodimethylsilyl)-2-methylpropane; 550OPF5Z9F; CHEBI:85071

Properties & Characteristics

Appearance: White hygroscopic solid; [Merck Index] White crystals with a pungent odor; [Alfa Aesar MSDS]. Molecular formula: C6H15ClSi. Molecular weight: 150.72 g/mol.

Physical Data

PropertyValue
Molecular Weight150.72
AppearanceWhite hygroscopic solid; [Merck Index] White crystals with a pungent odor; [Alfa Aesar MSDS]

Uses & Applications

Used as a synthetic reagent for transformations including oxidation, reduction, coupling, or functional group manipulation.

Safety Information

Hazardous reagent. May be toxic, corrosive, flammable, or reactive. Use in fume hood with full PPE. Consult SDS before use.

Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.

Key Facts

Term tert-Butyldimethylsilyl chloride
Formula C6H15ClSi
CAS Number 18162-48-6
Molecular Weight 150.72
Category Laboratory Reagents
Index All "T" terms
Synonyms tert-butyl-chloro-dimethylsilane; 18162-48-6; tert-Butyldimethylchlorosilane; t-Butyldimethylchlorosilane; TBDMS chloride; Silane, chloro(1,1-dimethylethyl)dimethyl-; Chloro-tert-butyldimethylsilane; 2-(chlorodimethylsilyl)-2-methylpropane; 550OPF5Z9F; CHEBI:85071

Frequently Asked Questions

Tert-butyldimethylsilyl chloride is a silyl chloride consisting of a central silicon atom covalently bound to one chloro, one tert-butyl and two methyl groups. tert-Butyldimethylsilyl chloride is a derivatisation agent used in gas chromatography/mass spectrometry applications. It has a role as a chromatographic reagent.

More "T" Terms

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Editorial standards: Chemical data is sourced from peer-reviewed literature, CAS Registry, NIST WebBook, and PubChem. Safety information reflects guidance from OSHA, ECHA, and IAEA. For educational purposes only — always consult official SDS documentation and qualified professionals before handling chemicals.

AllChemicals.info — The Online Chemical Glossary | https://allchemicals.info/chemical/tert-butyldimethylsilyl-chloride

For educational purposes only. Verify all information before use.