Heterocyclic Amine
| Also Known As | Heterocycle, N-heterocycle, nitrogen heterocycle, cyclic amine |
|---|
What is Heterocyclic Amine?
A heterocyclic amine is a cyclic organic compound in which the ring contains at least one nitrogen atom (and possibly other heteroatoms like oxygen or sulfur) as part of the ring structure. They are a major class of organic compounds including many biologically important molecules such as pyridine, pyrimidine, imidazole, purine, and indole. Heterocyclic amines are also formed when meat is cooked at high temperatures.
Properties & Characteristics
Uses & Applications
Safety Information
Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.
Key Facts
Frequently Asked Questions
A heterocyclic amine is a cyclic organic compound in which the ring contains at least one nitrogen atom (and possibly other heteroatoms like oxygen or sulfur) as part of the ring structure. They are a major class of organic compounds including many biologically important molecules such as pyridine, pyrimidine, imidazole, purine, and indole. Heterocyclic amines are also formed when meat is cooked at high temperatures.
Pharmaceutical chemistry (most drugs contain heterocyclic rings). DNA bases (adenine, guanine, cytosine, thymine, uracil are heterocycles). Vitamins (niacin, riboflavin, thiamine). Natural alkaloids (caffeine, morphine, nicotine). Pesticides and agrochemicals. Dyes and pigments. Polymer synthesis.
Highly variable toxicity. HCAs formed in cooked meat (MeIQx, PhIP) are carcinogenic mutagens. Many pharmaceutical HCAs have known toxicity profiles. DNA bases are benign at physiological levels. Some HCAs (nicotine, caffeine) are mildly toxic at high doses. Industrial HCAs may be highly toxic.