C

Cholecalciferol

IUPAC: (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol

C27H44O Organic Compounds CAS 67-97-0
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Quick Reference
Formula / NotationC27H44O
CAS Number67-97-0
Molecular Weight384.6
Melting Point183 to 185 °F (NTP, 1992)
SolubilityInsoluble (NTP, 1992)
AppearanceVitamin d3 appears as fine colorless crystals. Water insoluble. (NTP, 1992)
Also Known As(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol; Vitamin D3; 67-97-0; Colecalciferol; Calciol; Oleovitamin D3; Ricketon; Deparal; Arachitol; Delsterol
CategoryOrganic Compounds

What is Cholecalciferol?

Calciol is a hydroxy seco-steroid that is (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene in which the pro-S hydrogen at position 3 has been replaced by a hydroxy group. It is the inactive form of vitamin D3, being hydroxylated in the liver to calcidiol (25-hydroxyvitamin D3), which is then further hydroxylated in the kidney to give calcitriol (1,25-dihydroxyvitamin D3), the active hormone. It has a role as a geroprotector and a human metabolite. It is a steroid hormone, a secondary alcohol, a seco-cholestane, a hydroxy seco-steroid and a member of D3 vitamins.

Formula & Notation

C27H44O

IUPAC Name: (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol

Other Names / Synonyms: (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol; Vitamin D3; 67-97-0; Colecalciferol; Calciol; Oleovitamin D3; Ricketon; Deparal; Arachitol; Delsterol

Properties & Characteristics

Appearance: Vitamin d3 appears as fine colorless crystals. Water insoluble. (NTP, 1992). Molecular formula: C27H44O. Molecular weight: 384.6 g/mol. Melting point: 183 to 185 °F (NTP, 1992). Solubility: Insoluble (NTP, 1992). LogP: 7.9.

Physical Data

PropertyValue
Melting Point183 to 185 °F (NTP, 1992)
Molecular Weight384.6
SolubilityInsoluble (NTP, 1992)
AppearanceVitamin d3 appears as fine colorless crystals. Water insoluble. (NTP, 1992)

Uses & Applications

Used as an industrial feedstock, solvent, pharmaceutical intermediate, flavoring agent, or chemical building block.

Safety Information

Flammable or irritant. Many organic compounds are flammable liquids or vapours. Keep away from ignition sources. Consult SDS for specific hazard data.

Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.

Key Facts

Term Cholecalciferol
Formula C27H44O
CAS Number 67-97-0
Molecular Weight 384.6
Synonyms (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol; Vitamin D3; 67-97-0; Colecalciferol; Calciol; Oleovitamin D3; Ricketon; Deparal; Arachitol; Delsterol

Frequently Asked Questions

Calciol is a hydroxy seco-steroid that is (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene in which the pro-S hydrogen at position 3 has been replaced by a hydroxy group. It is the inactive form of vitamin D3, being hydroxylated in the liver to calcidiol (25-hydroxyvitamin D3), which is then further hydroxylated in the kidney to give calcitriol (1,25-dihydroxyvitamin D3), the active hormone. It has a role as a geroprotector and a human metabolite. It is a steroid hormone, a secondary alcohol, a seco-cholestane, a hydroxy seco-steroid and a member of D3 vitamins.

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Editorial standards: Chemical data is sourced from peer-reviewed literature, CAS Registry, NIST WebBook, and PubChem. Safety information reflects guidance from OSHA, ECHA, and IAEA. For educational purposes only — always consult official SDS documentation and qualified professionals before handling chemicals.