T

Thyroxine

IUPAC: (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid

C15H11I4NO4 Organic Compounds CAS 51-48-9
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Quick Reference
Formula / NotationC15H11I4NO4
CAS Number51-48-9
Molecular Weight776.87
Melting Point235.5 °C
Solubility0.105 mg/mL
AppearanceSolid
Also Known As(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid; thyroxin; L Thyroxin beta; L Thyrox; L Thyroxine Roche; L Thyroxin Henning; Levothyroxin Delalande; RefChem:5946; L-3,5,5'-tetraiodothyronine; 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid
CategoryOrganic Compounds

What is Thyroxine?

L-thyroxine is the L-enantiomer of thyroxine. It has a role as an antithyroid drug, a thyroid hormone, a mouse metabolite and a human metabolite. It is an iodophenol, a thyroxine, a 2-halophenol, a non-proteinogenic L-alpha-amino acid and a L-phenylalanine derivative. It is a conjugate acid of a L-thyroxine(1-). It is an enantiomer of a D-thyroxine. It is a tautomer of a L-thyroxine zwitterion.

Formula & Notation

C15H11I4NO4

IUPAC Name: (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid

Other Names / Synonyms: (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid; thyroxin; L Thyroxin beta; L Thyrox; L Thyroxine Roche; L Thyroxin Henning; Levothyroxin Delalande; RefChem:5946; L-3,5,5'-tetraiodothyronine; 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid

Properties & Characteristics

Appearance: Solid. Molecular formula: C15H11I4NO4. Molecular weight: 776.87 g/mol. Melting point: 235.5 °C. Solubility: 0.105 mg/mL. LogP: 2.4.

Physical Data

PropertyValue
Melting Point235.5 °C
Molecular Weight776.87
Solubility0.105 mg/mL
AppearanceSolid

Uses & Applications

Used as an industrial feedstock, solvent, pharmaceutical intermediate, flavoring agent, or chemical building block.

Safety Information

Flammable or irritant. Many organic compounds are flammable liquids or vapours. Keep away from ignition sources. Consult SDS for specific hazard data.

Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.

Key Facts

Term Thyroxine
Formula C15H11I4NO4
CAS Number 51-48-9
Molecular Weight 776.87
Synonyms (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid; thyroxin; L Thyroxin beta; L Thyrox; L Thyroxine Roche; L Thyroxin Henning; Levothyroxin Delalande; RefChem:5946; L-3,5,5'-tetraiodothyronine; 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid

Frequently Asked Questions

L-thyroxine is the L-enantiomer of thyroxine. It has a role as an antithyroid drug, a thyroid hormone, a mouse metabolite and a human metabolite. It is an iodophenol, a thyroxine, a 2-halophenol, a non-proteinogenic L-alpha-amino acid and a L-phenylalanine derivative. It is a conjugate acid of a L-thyroxine(1-). It is an enantiomer of a D-thyroxine. It is a tautomer of a L-thyroxine zwitterion.

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Editorial standards: Chemical data is sourced from peer-reviewed literature, CAS Registry, NIST WebBook, and PubChem. Safety information reflects guidance from OSHA, ECHA, and IAEA. For educational purposes only — always consult official SDS documentation and qualified professionals before handling chemicals.