C

Capsaicin

IUPAC: (E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide

C18H27NO3 Organic Compounds CAS 404-86-4
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Quick Reference
Formula / NotationC18H27NO3
CAS Number404-86-4
Molecular Weight305.4
Melting Point65
Boiling Point210-220
SolubilityInsoluble in cold water
AppearanceDark red solid with a volatile pungent odor; [HSDB] Formulated as dry powder, liquid, and liquid spray; [Reference #1] White crystalline solid; [Sigma-Aldrich MSDS]
Also Known As(E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide; 404-86-4; Zostrix; CAPSAICINE; Qutenza; trans-Capsaicin; Styptysat; Axsain; Isodecenoic acid vanillylamide; Ausanil
CategoryOrganic Compounds

What is Capsaicin?

Capsaicin is a capsaicinoid. It has a role as a TRPV1 agonist, a non-narcotic analgesic and a voltage-gated sodium channel blocker.

Formula & Notation

C18H27NO3

IUPAC Name: (E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide

Other Names / Synonyms: (E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide; 404-86-4; Zostrix; CAPSAICINE; Qutenza; trans-Capsaicin; Styptysat; Axsain; Isodecenoic acid vanillylamide; Ausanil

Properties & Characteristics

Appearance: Dark red solid with a volatile pungent odor; [HSDB] Formulated as dry powder, liquid, and liquid spray; [Reference #1] White crystalline solid; [Sigma-Aldrich MSDS]. Molecular formula: C18H27NO3. Molecular weight: 305.4 g/mol. Boiling point: 210-220. Melting point: 65. Solubility: Insoluble in cold water. Vapor pressure: 0.00000001 [mmHg]. LogP: 3.6.

Physical Data

PropertyValue
Melting Point65
Boiling Point210-220
Molecular Weight305.4
SolubilityInsoluble in cold water
AppearanceDark red solid with a volatile pungent odor; [HSDB] Formulated as dry powder, liquid, and liquid spray; [Reference #1] White crystalline solid; [Sigma-Aldrich MSDS]

Uses & Applications

Used as an industrial feedstock, solvent, pharmaceutical intermediate, flavoring agent, or chemical building block.

Safety Information

Flammable or irritant. Many organic compounds are flammable liquids or vapours. Keep away from ignition sources. Consult SDS for specific hazard data.

Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.

Key Facts

Term Capsaicin
Formula C18H27NO3
CAS Number 404-86-4
Molecular Weight 305.4
Synonyms (E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide; 404-86-4; Zostrix; CAPSAICINE; Qutenza; trans-Capsaicin; Styptysat; Axsain; Isodecenoic acid vanillylamide; Ausanil

Frequently Asked Questions

Capsaicin is a capsaicinoid. It has a role as a TRPV1 agonist, a non-narcotic analgesic and a voltage-gated sodium channel blocker.

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Editorial standards: Chemical data is sourced from peer-reviewed literature, CAS Registry, NIST WebBook, and PubChem. Safety information reflects guidance from OSHA, ECHA, and IAEA. For educational purposes only — always consult official SDS documentation and qualified professionals before handling chemicals.