B

Bromophenol blue

IUPAC: 2,6-dibromo-4-[3-(3,5-dibromo-4-hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol

C19H10Br4O5S Indicators CAS 115-39-9
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Quick Reference
Formula / NotationC19H10Br4O5S
CAS Number115-39-9
Molecular Weight670.0
Melting PointDecomposes at 279 °C (An orange discoloration with formation of a green sublimate sets in at 210 °C)
SolubilitySoluble in acetic acid
AppearanceOdorless solid; Color varies (tan, orange, light pink, purple, or red) [CHEMINFO] Slightly soluble in water; [MSDSonline]
Also Known As2,6-dibromo-4-[3-(3,5-dibromo-4-hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol; 115-39-9; BROMPHENOL BLUE; Albutest; Tetrabromphenol Blue; 3,3',5,5'-Tetrabromophenolsulfonphthalein; 3',3'',5',5''-Tetrabromophenolsulfonephthalein; DTXSID6041682; NSC-7818; 3',3'',5',5''-Tetrabromophenolsulfophthalein
CategoryIndicators

What is Bromophenol blue?

Bromophenol blue is 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 3,5-dibromo-4-hydroxyphenyl groups. It is used as a laboratory indicator, changing from yellow below pH 3 to purple at pH 4.6, and as a size marker for monitoring the progress of agarose gel and polyacrylamide gel electrophoresis. It has also been used as an industrial dye. It has a role as a dye, an acid-base indicator and a two-colour indicator. It is a member of phenols, an organobromine compound, a 2,1-benzoxathiole, a sultone and an arenesulfonate ester.

Formula & Notation

C19H10Br4O5S

IUPAC Name: 2,6-dibromo-4-[3-(3,5-dibromo-4-hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol

Other Names / Synonyms: 2,6-dibromo-4-[3-(3,5-dibromo-4-hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol; 115-39-9; BROMPHENOL BLUE; Albutest; Tetrabromphenol Blue; 3,3',5,5'-Tetrabromophenolsulfonphthalein; 3',3'',5',5''-Tetrabromophenolsulfonephthalein; DTXSID6041682; NSC-7818; 3',3'',5',5''-Tetrabromophenolsulfophthalein

Properties & Characteristics

Appearance: Odorless solid; Color varies (tan, orange, light pink, purple, or red) [CHEMINFO] Slightly soluble in water; [MSDSonline]. Molecular formula: C19H10Br4O5S. Molecular weight: 670.0 g/mol. Melting point: Decomposes at 279 °C (An orange discoloration with formation of a green sublimate sets in at 210 °C). Solubility: Soluble in acetic acid. LogP: 5.8.

Physical Data

PropertyValue
Melting PointDecomposes at 279 °C (An orange discoloration with formation of a green sublimate sets in at 210 °C)
Molecular Weight670.0
SolubilitySoluble in acetic acid
AppearanceOdorless solid; Color varies (tan, orange, light pink, purple, or red) [CHEMINFO] Slightly soluble in water; [MSDSonline]

Uses & Applications

Used as a pH indicator in acid-base titrations, analytical chemistry, and chemical education demonstrations.

Safety Information

May be irritant or toxic in concentrated form. Handle with care. Consult SDS before use.

Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.

Key Facts

Term Bromophenol blue
Formula C19H10Br4O5S
CAS Number 115-39-9
Molecular Weight 670.0
Category Indicators
Synonyms 2,6-dibromo-4-[3-(3,5-dibromo-4-hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol; 115-39-9; BROMPHENOL BLUE; Albutest; Tetrabromphenol Blue; 3,3',5,5'-Tetrabromophenolsulfonphthalein; 3',3'',5',5''-Tetrabromophenolsulfonephthalein; DTXSID6041682; NSC-7818; 3',3'',5',5''-Tetrabromophenolsulfophthalein

Frequently Asked Questions

Bromophenol blue is 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 3,5-dibromo-4-hydroxyphenyl groups. It is used as a laboratory indicator, changing from yellow below pH 3 to purple at pH 4.6, and as a size marker for monitoring the progress of agarose gel and polyacrylamide gel electrophoresis. It has also been used as an industrial dye. It has a role as a dye, an acid-base indicator and a two-colour indicator. It is a member of phenols, an organobromine compound, a 2,1-benzoxathiole, a sultone and an arenesulfonate ester.

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Editorial standards: Chemical data is sourced from peer-reviewed literature, CAS Registry, NIST WebBook, and PubChem. Safety information reflects guidance from OSHA, ECHA, and IAEA. For educational purposes only — always consult official SDS documentation and qualified professionals before handling chemicals.