T

Trifluoroacetic acid

IUPAC: 2,2,2-trifluoroacetic acid

C2HF3O2 Acids CAS 76-05-1
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Quick Reference
Formula / NotationC2HF3O2
CAS Number76-05-1
Molecular Weight114.02
Melting Point-15.4 °C
Boiling Point72.4 °C
Density1.531 at 20 °C
SolubilityMiscible with ether, acetone, ethanol, benzene, carbon tetrachloride, hexane.
AppearanceTrifluoroacetic acid appears as a colorless fuming liquid with a pungent odor. Soluble in water and denser than water. Corrosive to skin, eyes and mucous membranes. Used to make other chemicals and...
Also Known As2,2,2-trifluoroacetic acid; 76-05-1; Perfluoroacetic acid; Trifluoracetic acid; Trifluoroethanoic acid; Acetic acid, trifluoro-; Kyselina trifluoroctova; Acetic acid, 2,2,2-trifluoro-; DTXSID9041578; E5R8Z4G708
CategoryAcids

What is Trifluoroacetic acid?

Trifluoroacetic acid is a monocarboxylic acid that is the trifluoro derivative of acetic acid. It has a role as a reagent and a human xenobiotic metabolite. It is functionally related to an acetic acid. It is a conjugate acid of a trifluoroacetate.

Formula & Notation

C2HF3O2

IUPAC Name: 2,2,2-trifluoroacetic acid

Other Names / Synonyms: 2,2,2-trifluoroacetic acid; 76-05-1; Perfluoroacetic acid; Trifluoracetic acid; Trifluoroethanoic acid; Acetic acid, trifluoro-; Kyselina trifluoroctova; Acetic acid, 2,2,2-trifluoro-; DTXSID9041578; E5R8Z4G708

Properties & Characteristics

Appearance: Trifluoroacetic acid appears as a colorless fuming liquid with a pungent odor. Soluble in water and denser than water. Corrosive to skin, eyes and mucous membranes. Used to make other chemicals and.... Molecular formula: C2HF3O2. Molecular weight: 114.02 g/mol. Boiling point: 72.4 °C. Melting point: -15.4 °C. Density: 1.531 at 20 °C. Solubility: Miscible with ether, acetone, ethanol, benzene, carbon tetrachloride, hexane.. Vapor pressure: 110.0 [mmHg]. LogP: 0.9.

Physical Data

PropertyValue
Melting Point-15.4 °C
Boiling Point72.4 °C
Density1.531 at 20 °C
Molecular Weight114.02
SolubilityMiscible with ether, acetone, ethanol, benzene, carbon tetrachloride, hexane.
AppearanceTrifluoroacetic acid appears as a colorless fuming liquid with a pungent odor. Soluble in water and denser than water. Corrosive to skin, eyes and mucous membranes. Used to make other chemicals and...

Uses & Applications

Used in industrial chemical synthesis, fertilizer production, battery electrolytes, metal processing, and laboratory acid-base reactions.

Safety Information

Corrosive. Causes severe burns to skin, eyes, and respiratory tract. Wear appropriate PPE including gloves, goggles, and lab coat. Consult SDS before use.

Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.

Key Facts

Term Trifluoroacetic acid
Formula C2HF3O2
CAS Number 76-05-1
Molecular Weight 114.02
Category Acids
Synonyms 2,2,2-trifluoroacetic acid; 76-05-1; Perfluoroacetic acid; Trifluoracetic acid; Trifluoroethanoic acid; Acetic acid, trifluoro-; Kyselina trifluoroctova; Acetic acid, 2,2,2-trifluoro-; DTXSID9041578; E5R8Z4G708

Frequently Asked Questions

Trifluoroacetic acid is a monocarboxylic acid that is the trifluoro derivative of acetic acid. It has a role as a reagent and a human xenobiotic metabolite. It is functionally related to an acetic acid. It is a conjugate acid of a trifluoroacetate.

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Editorial standards: Chemical data is sourced from peer-reviewed literature, CAS Registry, NIST WebBook, and PubChem. Safety information reflects guidance from OSHA, ECHA, and IAEA. For educational purposes only — always consult official SDS documentation and qualified professionals before handling chemicals.