P

Pyroglutamic acid

IUPAC: (2S)-5-oxopyrrolidine-2-carboxylic acid

C5H7NO3 Acids CAS 98-79-3
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Quick Reference
Formula / NotationC5H7NO3
CAS Number98-79-3
Molecular Weight129.11
Melting Point184.7 °C
Solubility476000 mg/L (at 13 °C)
AppearanceSolid; [Merck Index] White crystalline powder; [Alfa Aesar MSDS]
Also Known As(2S)-5-oxopyrrolidine-2-carboxylic acid; L-Pyroglutamic acid; 98-79-3; Pidolic acid; 5-oxo-L-proline; pyroglu; GLUTIMIC ACID; (S)-(-)-2-Pyrrolidone-5-carboxylic acid; 5-L-Oxoproline; L-Proline, 5-oxo-
CategoryAcids

What is Pyroglutamic acid?

5-oxo-L-proline is an optically active form of 5-oxoproline having L-configuration. It has a role as an algal metabolite. It is a 5-oxoproline, a non-proteinogenic L-alpha-amino acid and a L-proline derivative. It is a conjugate acid of a 5-oxo-L-prolinate. It is an enantiomer of a 5-oxo-D-proline.

Formula & Notation

C5H7NO3

IUPAC Name: (2S)-5-oxopyrrolidine-2-carboxylic acid

Other Names / Synonyms: (2S)-5-oxopyrrolidine-2-carboxylic acid; L-Pyroglutamic acid; 98-79-3; Pidolic acid; 5-oxo-L-proline; pyroglu; GLUTIMIC ACID; (S)-(-)-2-Pyrrolidone-5-carboxylic acid; 5-L-Oxoproline; L-Proline, 5-oxo-

Properties & Characteristics

Appearance: Solid; [Merck Index] White crystalline powder; [Alfa Aesar MSDS]. Molecular formula: C5H7NO3. Molecular weight: 129.11 g/mol. Melting point: 184.7 °C. Solubility: 476000 mg/L (at 13 °C). LogP: -0.8.

Physical Data

PropertyValue
Melting Point184.7 °C
Molecular Weight129.11
Solubility476000 mg/L (at 13 °C)
AppearanceSolid; [Merck Index] White crystalline powder; [Alfa Aesar MSDS]

Uses & Applications

Used in industrial chemical synthesis, fertilizer production, battery electrolytes, metal processing, and laboratory acid-base reactions.

Safety Information

Corrosive. Causes severe burns to skin, eyes, and respiratory tract. Wear appropriate PPE including gloves, goggles, and lab coat. Consult SDS before use.

Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.

Key Facts

Term Pyroglutamic acid
Formula C5H7NO3
CAS Number 98-79-3
Molecular Weight 129.11
Category Acids
Synonyms (2S)-5-oxopyrrolidine-2-carboxylic acid; L-Pyroglutamic acid; 98-79-3; Pidolic acid; 5-oxo-L-proline; pyroglu; GLUTIMIC ACID; (S)-(-)-2-Pyrrolidone-5-carboxylic acid; 5-L-Oxoproline; L-Proline, 5-oxo-

Frequently Asked Questions

5-oxo-L-proline is an optically active form of 5-oxoproline having L-configuration. It has a role as an algal metabolite. It is a 5-oxoproline, a non-proteinogenic L-alpha-amino acid and a L-proline derivative. It is a conjugate acid of a 5-oxo-L-prolinate. It is an enantiomer of a 5-oxo-D-proline.

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Editorial standards: Chemical data is sourced from peer-reviewed literature, CAS Registry, NIST WebBook, and PubChem. Safety information reflects guidance from OSHA, ECHA, and IAEA. For educational purposes only — always consult official SDS documentation and qualified professionals before handling chemicals.