Acyl Group
| Formula / Notation | R-C(=O)- or RCO- |
|---|---|
| Also Known As | Acyl radical; RCO group; carbonyl group (as substituent); acetyl group (when R = CH₃) |
What is Acyl Group?
An acyl group is a functional group derived from a carboxylic acid by the removal of a hydroxyl (–OH) group, leaving a carbonyl group (C=O) bonded to one organic substituent (R). The general formula is RCO–. Acyl groups are important in the formation of esters, amides, acid chlorides, and acid anhydrides.
Formula & Notation
Other Names / Synonyms: Acyl radical; RCO group; carbonyl group (as substituent); acetyl group (when R = CH₃)
Properties & Characteristics
Uses & Applications
Safety Information
Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.
Key Facts
Frequently Asked Questions
An acyl group is a functional group derived from a carboxylic acid by the removal of a hydroxyl (–OH) group, leaving a carbonyl group (C=O) bonded to one organic substituent (R). The general formula is RCO–. Acyl groups are important in the formation of esters, amides, acid chlorides, and acid anhydrides.
Key functional group in organic synthesis for forming esters, amides, anhydrides, and acid halides; acetyl group important in biochemistry (acetylation of proteins and DNA); benzoyl group in pharmaceutical synthesis; formyl group in aldehyde chemistry
Acyl-containing compounds are often reactive and may be corrosive or toxic. Acid chlorides (containing RCO–Cl) are highly reactive with water and corrosive. Handle acyl compounds with appropriate PPE and in a fume hood.
The formula or notation for Acyl Group is: R-C(=O)- or RCO-