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Xylidine

(CH₃)₂C₆H₃NH₂
Quick Reference
Formula / Notation(CH₃)₂C₆H₃NH₂
Also Known AsDimethylaniline (amine isomers), aminoxylene, dimethylaminobenzene

What is Xylidine?

Any of six isomeric compounds with the formula (CH₃)₂C₆H₃NH₂, derived from xylenol by replacing a hydroxyl group with an amino group. Xylidines are used as intermediates in the production of dyes and pharmaceuticals. They are toxic and require careful handling.

Formula & Notation

(CH₃)₂C₆H₃NH₂

Other Names / Synonyms: Dimethylaniline (amine isomers), aminoxylene, dimethylaminobenzene

Properties & Characteristics

Xylidine is any of the six isomeric aromatic amines derived from xylene by replacing one ring hydrogen with an amino group, giving the formula (CH₃)₂C₆H₃NH₂. They are colourless to pale yellow oily liquids with a weak amine odour. Xylidines are weakly basic aromatic amines soluble in organic solvents. The most common commercial mixture is 2,4-xylidine.

Uses & Applications

Xylidines are used as intermediates in the synthesis of azo dyes, pharmaceuticals, and agricultural chemicals. 2,6-xylidine is the precursor to the local anaesthetic lidocaine. Xylidine derivatives are used in the manufacture of flavours, fragrances, and rubber chemicals.

Safety Information

Xylidines are toxic by inhalation, ingestion, and skin absorption. They can cause methaemoglobinaemia (reduced oxygen transport in blood) similar to aniline. Some xylidine isomers are considered probable carcinogens and must be handled with appropriate respiratory and skin protection.

Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.

Key Facts

Term Xylidine
Formula (CH₃)₂C₆H₃NH₂
Synonyms Dimethylaniline (amine isomers), aminoxylene, dimethylaminobenzene

Frequently Asked Questions

Any of six isomeric compounds with the formula (CH₃)₂C₆H₃NH₂, derived from xylenol by replacing a hydroxyl group with an amino group. Xylidines are used as intermediates in the production of dyes and pharmaceuticals. They are toxic and require careful handling.

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