Cis
| Also Known As | Cis isomer, Z-isomer (CIP rules), syn (in some naming systems) |
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What is Cis?
Cis is a Latin prefix meaning "on the same side", used in chemistry to describe geometric isomers in which identical or similar substituents are on the same side of a double bond or ring. In cis-2-butene, both methyl groups are on the same side of the C=C double bond, contrasting with the trans isomer where they are on opposite sides.
Properties & Characteristics
Uses & Applications
Safety Information
Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.
Key Facts
Frequently Asked Questions
Cis is a Latin prefix meaning "on the same side", used in chemistry to describe geometric isomers in which identical or similar substituents are on the same side of a double bond or ring. In cis-2-butene, both methyl groups are on the same side of the C=C double bond, contrasting with the trans isomer where they are on opposite sides.
The cis/trans distinction is critical in biochemistry: cis-fatty acids (unsaturated, kinked chains) are liquid at room temperature, while trans-fatty acids behave like saturated fats and are linked to cardiovascular disease. Cis-platinum (cisplatin) is an anticancer drug; its trans isomer is inactiv…
Some cis isomers are significantly more toxic or pharmacologically active than their trans counterparts. Always verify the specific isomer when working with drugs, natural products, or environmental contaminants. Trans-fatty acid consumption is regulated in many countries.