Amide
| Formula / Notation | −CONH− (amide linkage) | RCONH₂ (primary), RCONHR' (secondary) |
|---|---|
| Also Known As | Carboxamide, Acid amide, Peptide bond (in proteins) |
What is Amide?
An amide is an organic functional group or compound containing a carbonyl group (C=O) bonded to a nitrogen atom. Amides are formed by the reaction of carboxylic acids with amines, and are found in proteins (peptide bonds), nylon, and many pharmaceuticals. They are generally less reactive than other carbonyl compounds.
Formula & Notation
Other Names / Synonyms: Carboxamide, Acid amide, Peptide bond (in proteins)
Properties & Characteristics
Uses & Applications
Safety Information
Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.
Key Facts
Frequently Asked Questions
An amide is an organic functional group or compound containing a carbonyl group (C=O) bonded to a nitrogen atom. Amides are formed by the reaction of carboxylic acids with amines, and are found in proteins (peptide bonds), nylon, and many pharmaceuticals. They are generally less reactive than other carbonyl compounds.
Nylon polyamides (Nylon-6,6 from hexanediamine + adipic acid) for textiles, ropes, engineering plastics. Kevlar (para-aramid): bulletproof vests, high-strength composites. Urea (H₂NCONH₂): nitrogen fertilizer, urea-formaldehyde resins, protein metabolism product. Dimethylformamide (DMF): industrial …
Formamide and DMF are reproductive toxins (teratogenic) — avoid exposure during pregnancy. N,N-Dimethylformamide penetrates skin rapidly. Acrylamide (used in gel electrophoresis) is a neurotoxin and probable carcinogen — handle with gloves. Urea is relatively safe. β-Lactam antibiotics cause allergi…
The formula or notation for Amide is: −CONH− (amide linkage) | RCONH₂ (primary), RCONHR' (secondary)