Acid Anhydride
| Formula / Notation | R-CO-O-CO-R' (general) |
|---|---|
| Also Known As | Carboxylic acid anhydride; organic anhydride; RCO-O-COR |
What is Acid Anhydride?
An acid anhydride is a compound formed by the condensation of two carboxylic acid molecules with the loss of one water molecule. The resulting compound contains two acyl groups joined by an oxygen atom. Acid anhydrides react readily with water (hydrolysis), alcohols (esterification), and amines (amide formation).
Formula & Notation
Other Names / Synonyms: Carboxylic acid anhydride; organic anhydride; RCO-O-COR
Properties & Characteristics
Uses & Applications
Safety Information
Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.
Key Facts
Frequently Asked Questions
An acid anhydride is a compound formed by the condensation of two carboxylic acid molecules with the loss of one water molecule. The resulting compound contains two acyl groups joined by an oxygen atom. Acid anhydrides react readily with water (hydrolysis), alcohols (esterification), and amines (amide formation).
Acylating agents in organic synthesis; production of esters, amides, and pharmaceuticals; synthesis of aspirin (acetylation of salicylic acid); as dehydrating agents; manufacture of dyes and polymers
Corrosive and reactive — acetic anhydride causes severe skin and eye burns. Reacts vigorously with water. Flammable (flash point: 54°C). Use in a fume hood with appropriate PPE. Some acid anhydrides are highly toxic.
The formula or notation for Acid Anhydride is: R-CO-O-CO-R' (general)