P

Propofol

IUPAC: 2,6-di(propan-2-yl)phenol

C12H18O Organic Compounds CAS 2078-54-8
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Quick Reference
Formula / NotationC12H18O
CAS Number2078-54-8
Molecular Weight178.27
Melting Point18 °C
Boiling Point256 °C
Density0.955 g/cu cm @ 20 °C
Solubility124 mg/L
AppearanceLiquid
Also Known As2,6-di(propan-2-yl)phenol; 2,6-DIISOPROPYLPHENOL; 2078-54-8; Diprivan; Disoprofol; Disoprivan; Fresofol; Rapinovet; Ampofol; 2,6-Bis(1-methylethyl)phenol
CategoryOrganic Compounds

What is Propofol?

Propofol is a phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group. It has a role as an anticonvulsant, a sedative, an intravenous anaesthetic, a radical scavenger and an antiemetic.

Formula & Notation

C12H18O

IUPAC Name: 2,6-di(propan-2-yl)phenol

Other Names / Synonyms: 2,6-di(propan-2-yl)phenol; 2,6-DIISOPROPYLPHENOL; 2078-54-8; Diprivan; Disoprofol; Disoprivan; Fresofol; Rapinovet; Ampofol; 2,6-Bis(1-methylethyl)phenol

Properties & Characteristics

Appearance: Liquid. Molecular formula: C12H18O. Molecular weight: 178.27 g/mol. Boiling point: 256 °C. Melting point: 18 °C. Density: 0.955 g/cu cm @ 20 °C. Solubility: 124 mg/L. LogP: 3.8.

Physical Data

PropertyValue
Melting Point18 °C
Boiling Point256 °C
Density0.955 g/cu cm @ 20 °C
Molecular Weight178.27
Solubility124 mg/L
AppearanceLiquid

Uses & Applications

Used as an industrial feedstock, solvent, pharmaceutical intermediate, flavoring agent, or chemical building block.

Safety Information

Flammable or irritant. Many organic compounds are flammable liquids or vapours. Keep away from ignition sources. Consult SDS for specific hazard data.

Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.

Key Facts

Term Propofol
Formula C12H18O
CAS Number 2078-54-8
Molecular Weight 178.27
Synonyms 2,6-di(propan-2-yl)phenol; 2,6-DIISOPROPYLPHENOL; 2078-54-8; Diprivan; Disoprofol; Disoprivan; Fresofol; Rapinovet; Ampofol; 2,6-Bis(1-methylethyl)phenol

Frequently Asked Questions

Propofol is a phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group. It has a role as an anticonvulsant, a sedative, an intravenous anaesthetic, a radical scavenger and an antiemetic.

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Editorial standards: Chemical data is sourced from peer-reviewed literature, CAS Registry, NIST WebBook, and PubChem. Safety information reflects guidance from OSHA, ECHA, and IAEA. For educational purposes only — always consult official SDS documentation and qualified professionals before handling chemicals.