| Formula / Notation | C5H9NO2 |
|---|---|
| CAS Number | 147-85-3 |
| Molecular Weight | 115.13 |
| Melting Point | 221 dec °C |
| Density | 1.064 at 24 °C |
| Solubility | 162000 mg/L (at 25 °C) |
| Appearance | Dry Powder |
| Also Known As | (2S)-pyrrolidine-2-carboxylic acid; 147-85-3; proline; L-(-)-Proline; (S)-Pyrrolidine-2-carboxylic acid; (-)-Proline; 2-pyrrolidinecarboxylic acid; (-)-(S)-Proline; (S)-2-Pyrrolidinecarboxylic acid; prolina |
| Category | Organic Compounds |
What is L-Proline?
L-proline is pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles. It has a role as a member of compatible osmolytes, a micronutrient, a nutraceutical, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and an algal metabolite. It is a L-alpha-amino acid, a glutamine family amino acid, a proline and a proteinogenic amino acid. It is a conjugate base of a L-prolinium. It is a conjugate acid of a L-prolinate. It is an enantiomer of a D-proline. It is a tautomer of a L-proline zwitterion.
Formula & Notation
IUPAC Name: (2S)-pyrrolidine-2-carboxylic acid
Other Names / Synonyms: (2S)-pyrrolidine-2-carboxylic acid; 147-85-3; proline; L-(-)-Proline; (S)-Pyrrolidine-2-carboxylic acid; (-)-Proline; 2-pyrrolidinecarboxylic acid; (-)-(S)-Proline; (S)-2-Pyrrolidinecarboxylic acid; prolina
Properties & Characteristics
Physical Data
| Property | Value |
|---|---|
| Melting Point | 221 dec °C |
| Density | 1.064 at 24 °C |
| Molecular Weight | 115.13 |
| Solubility | 162000 mg/L (at 25 °C) |
| Appearance | Dry Powder |
Uses & Applications
Safety Information
Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.
Key Facts
Frequently Asked Questions
L-proline is pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles. It has a role as a member of compatible osmolytes, a micronutrient, a nutraceutical, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and an algal metabolite. It is a L-alpha-amino acid, a glutamine family amino acid, a proline and a proteinogenic amino acid. It is a conjugate base of a L-prolinium. It is a conjugate acid of a L-prolinate. It is an enantiomer of a D-proline. It is a tautomer of a L-proline zwitterion.
Used as an industrial feedstock, solvent, pharmaceutical intermediate, flavoring agent, or chemical building block.
Flammable or irritant. Many organic compounds are flammable liquids or vapours. Keep away from ignition sources. Consult SDS for specific hazard data.
The formula or notation for L-Proline is: C5H9NO2