E

Estradiol

IUPAC: (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol

C18H24O2 Organic Compounds CAS 50-28-2
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Quick Reference
Formula / NotationC18H24O2
CAS Number50-28-2
Molecular Weight272.4
Melting Point173
Boiling Point445.9±45.0
Solubility3.6 mg/L (at 27 °C)
AppearanceSolid
Also Known As(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol; beta-Estradiol; 50-28-2; 17beta-Estradiol; Oestradiol; Dihydrofolliculin; Estrace; Aquadiol; Diogynets; Divigel
CategoryOrganic Compounds

What is Estradiol?

17beta-estradiol is the 17beta-isomer of estradiol. It has a role as a geroprotector, an estrogen, an EC 1.2.3.1 (aldehyde oxidase) inhibitor, a mouse metabolite, a human metabolite and a Daphnia magna metabolite. It is an estradiol and a 17beta-hydroxy steroid.

Formula & Notation

C18H24O2

IUPAC Name: (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol

Other Names / Synonyms: (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol; beta-Estradiol; 50-28-2; 17beta-Estradiol; Oestradiol; Dihydrofolliculin; Estrace; Aquadiol; Diogynets; Divigel

Properties & Characteristics

Appearance: Solid. Molecular formula: C18H24O2. Molecular weight: 272.4 g/mol. Boiling point: 445.9±45.0. Melting point: 173. Solubility: 3.6 mg/L (at 27 °C). LogP: 4.

Physical Data

PropertyValue
Melting Point173
Boiling Point445.9±45.0
Molecular Weight272.4
Solubility3.6 mg/L (at 27 °C)
AppearanceSolid

Uses & Applications

Used as an industrial feedstock, solvent, pharmaceutical intermediate, flavoring agent, or chemical building block.

Safety Information

Flammable or irritant. Many organic compounds are flammable liquids or vapours. Keep away from ignition sources. Consult SDS for specific hazard data.

Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.

Key Facts

Term Estradiol
Formula C18H24O2
CAS Number 50-28-2
Molecular Weight 272.4
Synonyms (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol; beta-Estradiol; 50-28-2; 17beta-Estradiol; Oestradiol; Dihydrofolliculin; Estrace; Aquadiol; Diogynets; Divigel

Frequently Asked Questions

17beta-estradiol is the 17beta-isomer of estradiol. It has a role as a geroprotector, an estrogen, an EC 1.2.3.1 (aldehyde oxidase) inhibitor, a mouse metabolite, a human metabolite and a Daphnia magna metabolite. It is an estradiol and a 17beta-hydroxy steroid.

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Editorial standards: Chemical data is sourced from peer-reviewed literature, CAS Registry, NIST WebBook, and PubChem. Safety information reflects guidance from OSHA, ECHA, and IAEA. For educational purposes only — always consult official SDS documentation and qualified professionals before handling chemicals.