Substrate
| Formula / Notation | E + S ⇌ ES → E + P; Km = ([E][S])/[ES] |
|---|---|
| Also Known As | Enzyme substrate, reactant (biochemical), ligand (enzyme context) |
What is Substrate?
The molecule upon which an enzyme acts in a biochemical reaction. The substrate binds to the enzyme's active site, forming an enzyme-substrate complex. The enzyme catalyzes conversion of the substrate to product. Substrate concentration affects enzyme reaction rate (Michaelis-Menten kinetics).
Formula & Notation
Other Names / Synonyms: Enzyme substrate, reactant (biochemical), ligand (enzyme context)
Properties & Characteristics
Uses & Applications
Safety Information
Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.
Key Facts
Frequently Asked Questions
The molecule upon which an enzyme acts in a biochemical reaction. The substrate binds to the enzyme's active site, forming an enzyme-substrate complex. The enzyme catalyzes conversion of the substrate to product. Substrate concentration affects enzyme reaction rate (Michaelis-Menten kinetics).
Understanding substrate-enzyme interactions guides the design of enzyme inhibitors used as drugs. Substrate specificity is exploited in biosensors and diagnostic assays. Industrial biocatalysis uses enzymes with specific substrates to produce chemicals and pharmaceuticals.
Some substrates of industrial enzymes are toxic or mutagenic compounds. Handling enzyme substrates in research requires awareness of their specific hazards.
The formula or notation for Substrate is: E + S ⇌ ES → E + P; Km = ([E][S])/[ES]