Peptide Bond
| Formula / Notation | Peptide bond: -CO-NH-; formed by condensation: -COOH + H₂N- → -CO-NH- + H₂O |
|---|---|
| Also Known As | Amide bond (in peptide context), peptide linkage, polypeptide bond, −CO−NH− |
What is Peptide Bond?
A covalent bond formed between the carboxyl group of one amino acid and the amino group of another, with loss of water. Peptide bonds link amino acids together to form polypeptides and proteins. They have partial double-bond character due to resonance, restricting rotation.
Formula & Notation
Other Names / Synonyms: Amide bond (in peptide context), peptide linkage, polypeptide bond, −CO−NH−
Properties & Characteristics
Uses & Applications
Safety Information
Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.
Key Facts
Frequently Asked Questions
A covalent bond formed between the carboxyl group of one amino acid and the amino group of another, with loss of water. Peptide bonds link amino acids together to form polypeptides and proteins. They have partial double-bond character due to resonance, restricting rotation.
Peptide bonds form the backbone of all proteins and peptides, which perform virtually all biological functions. Synthetic peptides are used as pharmaceuticals (insulin, oxytocin, GnRH analogues), research tools (cell-penetrating peptides), and in food science (hydrolysed proteins as flavour enhancer…
No direct safety hazard from the peptide bond itself. Proteins containing toxic amino acid sequences (e.g., ricin, which contains a cytotoxic A chain) must be handled appropriately. Hydrolysis of proteins with concentrated HCl at 110°C (amino acid analysis) requires a sealed, pressure-rated vessel a…
The formula or notation for Peptide Bond is: Peptide bond: -CO-NH-; formed by condensation: -COOH + H₂N- → -CO-NH- + H₂O