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Nitrogenases

What is Nitrogenases?

Nitrogenases are metalloenzymes found in nitrogen-fixing microorganisms that catalyze the reduction of atmospheric nitrogen (N₂) to ammonia (NH₃) under ambient conditions, a process that requires significant ATP and is highly oxygen-sensitive. They contain complex metal cofactors, typically iron-molybdenum (FeMo-co) or iron-vanadium clusters, at their active sites. Nitrogenases are of intense research interest as models for developing more energy-efficient industrial nitrogen fixation catalysts to replace the energy-intensive Haber-Bosch process.

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Term Nitrogenases

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Nitrogenases are metalloenzymes found in nitrogen-fixing microorganisms that catalyze the reduction of atmospheric nitrogen (N₂) to ammonia (NH₃) under ambient conditions, a process that requires significant ATP and is highly oxygen-sensitive. They contain complex metal cofactors, typically iron-molybdenum (FeMo-co) or iron-vanadium clusters, at their active sites. Nitrogenases are of intense research interest as models for developing more energy-efficient industrial nitrogen fixation catalysts to replace the energy-intensive Haber-Bosch process.

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