Levorotatory
| Formula / Notation | (−)-rotation: [α]_D < 0; counterclockwise rotation of polarised light |
|---|---|
| Also Known As | (−)-rotation, laevorotatory, l-rotation, counterclockwise optical rotation |
What is Levorotatory?
A term describing an optically active compound that rotates plane-polarized light in a counterclockwise direction (to the left) when viewed facing the oncoming light. Designated with a (-) or l- prefix. The opposite of dextrorotatory.
Formula & Notation
Other Names / Synonyms: (−)-rotation, laevorotatory, l-rotation, counterclockwise optical rotation
Properties & Characteristics
Uses & Applications
Safety Information
Always consult the SDS/MSDS before handling any chemical. This information is for educational purposes only.
Key Facts
Frequently Asked Questions
A term describing an optically active compound that rotates plane-polarized light in a counterclockwise direction (to the left) when viewed facing the oncoming light. Designated with a (-) or l- prefix. The opposite of dextrorotatory.
Optical rotation measurements are used for: characterising chiral molecules, monitoring asymmetric synthesis reactions, determining enantiomeric excess (ee), quality control of pharmaceuticals and natural products (sugar analysis, amino acid configuration), and forensic identification of controlled …
Levorotatory enantiomers of certain drugs are more potent or more toxic than their dextrorotatory counterparts. Thalidomide: R-(+) is sedative, S-(−) is teratogenic. Regulation of chiral drugs requires both enantiomers to be assessed for safety and efficacy individually.
The formula or notation for Levorotatory is: (−)-rotation: [α]_D < 0; counterclockwise rotation of polarised light